How the T Cell Receptor Sees Antigen—A Structural View
نویسندگان
چکیده
Structures of many of the cell surface receptor-ligand complexes mediating the interactions between T cells and target cells have been determined in the past ten years. While snapshots of T cell receptors bound to their peptide-MHC ligands appear to have defined a general interaction or "docking" solution, many of the most fundamental structural questions in antigen recognition lack detailed answers and thus pose exciting experimental challenges for the future.
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عنوان ژورنال:
- Cell
دوره 122 شماره
صفحات -
تاریخ انتشار 2005